Schonny Winston flexed for La Salle with 23 points, 14 rebounds, five assists, and five steals.
Kevin Quiambao, who had a poster dunk over Daniel Celzo, tallied 16 points, eight rebounds, and four assists, while Manuel got 14 points.
Evan Nelle returned with an all-around eight points, 12 assists, six rebounds, and six steals.
The Green Archers, who missed Mike Phillips due to a minor right hamstring injury, is back above .500 at 3-2, good for fourth, while FEU slid to 0-5 – its worst start in the Final Four era.